A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/439 (2006.01) A61K 31/277 (2006.01) A61K 31/44 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01)
Patent
CA 2568566
A combination which comprises (a) a PDE4 inhibitor and (b) an antagonist of M3 muscarinic receptors which is 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1~(3- phenoxypropyl)-1-azoniabicyclo[2.2.2]octane, in the form of a salt having an anion X, which is a pharmaceutically acceptable anion of a mono or polyvalent acid.
Cette invention concerne une combinaison, qui comprend: (a) un inhibiteur de PDE4 et (b) un antagoniste de récepteurs muscariniques M3 constitué par 3(R)-(2-hydroxy-2,2-dithién-2-ylacétoxy)-1-(3-phénoxypropyl)-1-azoniabicyclo[2.2.2]octane, sous la forme d'un sel comportant un anion X, constitué par un anion pharmaceutiquement acceptable d'un acide monovalent ou polyvalent.
Gras Escardo Jordi
Llenas Calvo Jesus
Orviz Diaz Pio
Ryder Hamish
Almirall S.a.
Almirall Prodesfarma S.a.
Goudreau Gage Dubuc
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