A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/58 (2006.01) A61K 31/397 (2006.01) A61K 31/4439 (2006.01) A61K 31/445 (2006.01) A61K 31/4709 (2006.01) A61K 31/727 (2006.01) A61K 38/55 (2006.01)
Patent
CA 2602563
The present invention relates to novel pharmaceutical compositions comprising at least one direct thrombin inhibitor and at least one additional active compound selected from the groups consisting of platelet inhibitors, low molecular weight heparins (LMWH) and heparinoids as well as unfractionated heparin, factor Xa inhibitors, combined thrombin/factor Xa inhibitors, fibrinogen receptor antagonists (glycoprotein IIb/IIa antagonists) and Vitamin K antagonists, optionally together with one or more pharmaceutically acceptable excipients or carriers for the treatment of thrombosis.
L'invention concerne de nouvelles compositions pharmaceutiques qui contiennent au moins un inhibiteur direct de la thrombine et au moins un composé actif supplémentaire choisi dans les groupes constitués par les inhibiteurs de plaquettes, les héparinoïdes et les héparines de faible poids moléculaire (LMWH) ainsi que l'héparine non fractionnée, les inhibiteurs du facteur Xa, combinés aux inhibiteurs de la thrombine/facteur Xa, les antagonistes du récepteur du fibrinogène (antagonistes de la glycoprotéine IIb/IIa) ainsi que les antagonistes de la vitamine K, éventuellement associés à au moins un excipient pharmaceutiquement acceptable pour le traitement de la thrombose.
Gilbert James C.
Mueller Thomas H.
Reilly Paul A.
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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