Combinations comprising epothilones and protein tyrosine...

Details Combinations comprising epothilones and protein tyrosine... Combinations comprising epothilones and protein tyrosine...

A - Human Necessities

61

K

A61K 31/426 (2006.01) A61K 31/436 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2584163

The invention relates to a combination which comprises: (a) an epothilone; and (b) a protein tyrosine kinase inhibitor; and optionally (c) a derivative of rapamycin; for simultaneous, separate or sequential use, in particular, for the delay of progression or treatment of a proliferative disease, especially cancer.

La présente invention se rapporte à un produit composé qui contient : (a) une épothilone ; (b) un inhibiteur des protéines tyrosine kinases ; et éventuellement (c) un dérivé de la rapamycine. La combinaison selon l'invention est destinée à une utilisation simultanée, séparée ou séquentielle, en particulier pour retarder la progression d'une maladie proliférative, notamment le cancer, ou pour traiter une telle maladie.

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