Combinations comprising sorafenib and interferon for the...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 31/4412 (2006.01) A61K 38/21 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2627875

The present invention provides methods for treating cancer in humans and other mammals comprising administering a chemotherapeutic agent, such as an interferon, and an aryl urea compound of Formula (I) : B-NH-C(O)-NH-L-M-L1- (Q)1-3 (I). In Formula (I), B and L and are each, independently, optionally substituted phenyl, naphthyl, a 5 or 6 membered monocyclic heteroaryl group, or an 8 to 10 membered bicyclic heteroaryl group; M is a bridging group. Each Q is independently C(O)R4, C(O)OR4 and C(O)NR4R5; and L' is optionally substituted phenyl, naphthyl, monocyclic heteroaryl or bicyclic heteroaryl, or a saturated or partially saturated, monocyclic or bicyclic carbocyclic moiety or heterocyclic moiety.

L'invention concerne des méthodes de traitement du cancer chez des sujets humains et autres mammifères, qui consistent à administrer un agent chimiothérapeutique, de type interféron, et un composé aryle-urée de formule (I) : B-NH-C(O)-NH-L-M-L1-(Q)1-3 (I). Dans ladite formule (I), B et L représentent chacun, indépendamment, un groupe phényle, un groupe naphthyle, un groupe hétéroaryle bicyclique de 5 à 6 éléments, ou un groupe hétéroaryle bicyclique de 8 à 10 éléments éventuellement substitués; M représente un groupe de liaison; chaque Q représente indépendamment C(O)R4, C(O)OR4 et C(O)NR4R5; et L' représente phényle, naphthyle, hétéroaryle monocyclique ou hétéroaryle bicyclique, ou un fragment hétérocyclique ou un fragment carbocyclique monocyclique ou bicyclique saturé ou partiellement saturé éventuellement substitués.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Combinations comprising sorafenib and interferon for the... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Combinations comprising sorafenib and interferon for the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Combinations comprising sorafenib and interferon for the... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1454134

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.