Combinations for oral compositions, their preparation and use

A - Human Necessities – 61 – K

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A61K 8/49 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2658710

A composition having a pH in the range of from 3 to 8.5, comprising: (a) in the range of from 0.1 % to <10% w/w (based on the total weight of the composition) of a stock solution comprising a mixture of bioflavonoids and fruit acids or salts thereof; (b) sodium hyaluronate; and (c) water; and, optionally, (d) a pharmaceutically acceptable carrier therefor; wherein the sodium hyaluronate has an average molecular weight of between 800,000 and 4,000,000.

La présente invention concerne une composition dont le pH est compris entre 3 et 8,5 et qui comprend : (a) de 0,1 % à < 10 % poids/poids (sur la base du poids total de la composition) d'une solution mère comprenant un mélange de bio-flavonoïdes et d'acides de fruits ou leurs sels ; (b) un hyaluronate de sodium ; et (c) de l'eau ; et, facultativement, (d) un véhicule pharmaceutiquement acceptable de celle-ci ; le hyaluronate de sodium ayant une masse moléculaire moyenne comprise entre 800 000 et 4 000 000.

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