A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/496 (2006.01) A61K 31/404 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2523868
The present invention relates to a pharmaceutical combination for the treatment of diseases which involves cell proliferation, migration or apoptosis of myeloma cells, or angiogenesis. The invention also relates to a method for the treatment of said deseases, coomprising co-administration of effective amounts of specific active compounds and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of these specific compounds and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
L'invention concerne une combinaison pharmaceutique pour le traitement de maladies qui impliquent la prolifération cellulaire, la migration ou l'apoptose de cellules de myélome ou l'angiogénèse. L'invention concerne également un procédé pour traiter lesdites maladies, comprenant la co-administration de quantités efficaces de composés actifs sélectifs et/ou un co-traitement par radiothérapie, à un taux qui produit un effet additif et synergique. L'invention concerne en outre, l'utilisation combinée des composés spécifiques et/ou de la radiothérapie pour fabriquer les préparations de combinaisons pharmaceutiques correspondantes.
Baum Anke
Hilberg Frank
Munzert Gerd
Solca Flavio
Stefanic Martin Friedrich
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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