A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4985 (2006.01) A61K 31/435 (2006.01) A61K 31/4409 (2006.01) A61K 31/519 (2006.01)
Patent
CA 2576269
The present invention relates to a pharmaceutical composition for the treatment of diseases which involve cell proliferation. The invention also relates to a method for the treatment of said diseases, comprising co- administration of a compound 1 of Formula (I) wherein the groups L, R1, R2, R3, R4 and R5 have the meanings given in the claims and specification, optionally in form of its tautomers, racemates, enantiomers, diastereomers and the mixtures thereof and optionally in form of the pharmacologically acceptable acid addition salts, solvates, hydrates, polymorphs, physiologically functional derivatives or prodrugs thereof, and of an effective amount of an active compound 2 and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of a compound 1 of Formula (I) and of an effective amount of an active compound 2 and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
Cette invention a pour objet une composition pharmaceutique pour le traitement de maladies impliquant une prolifération cellulaire. Cette invention concerne également un procédé de traitement desdites maladies, comprenant la co-administration d~un composé 1 de Formule (I) (I) au sein de laquelle les groupes L, R1, R2, R3, R4 et R5 correspondent aux définitions données par les indications techniques, optionnellement sous leurs formes tautomères, racémates, énantiomères, diastéréomères et le mélange de ces produits, et optionnellement sous forme pharmaceutiquement acceptable de sels d~addition d~acide, de solvates, d~hydrates, de polymorphes de dérivés physiologiquement fonctionnels ou de promédicaments formés à base de ces produits, et d~une proportion considérable de composé actif 2 et/ou du co-traitement par radiothérapie, dans une proportion permettant d~obtenir un effet additif et coopératif, et l~utilisation combinée d~un composé 1 de Formule (I) et d~une proportion considérable d~un composé actif 2 et/ou d~une radiothérapie permettant la fabrication des préparations correspondantes de combinaison pharmaceutique.
Baum Anke
Munzert Gerd
Steegmaier Martin
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
LandOfFree
Combinations for the treatment of diseases involving cell... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Combinations for the treatment of diseases involving cell..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Combinations for the treatment of diseases involving cell... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2079009