Combinations for the treatment of parkinsonism containing...

A - Human Necessities – 61 – K

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A61K 31/445 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2219911

This invention relates to a method of treating Parkinson's Disease whereby a mammal suffering from Parkinson's Disease is treated with a combination of a forebrain selective NMDA antagonist and a compound which is capable of increasing the excitatory feedback from the ventral lateral nucleus of the thalamus into the cortex. This invention also relates to pharmaceutical compositions containing the synergistic combination.

Procédé de traitement de la maladie de Parkinson selon lequel un mammifère atteint de la maladie de Parkinson est traité avec une combinaison d'un antagoniste de N-méthyle-D-aspartate sélectif de prosencéphale et d'un composé capable d'augmenter la rétroaction excitatrice du noyau ventral latéral du thalamus dans le cortex. La présente invention concerne également des compositions pharmaceutiques contenant ladite combinaison synergique.

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