Combinations of a pyrimidine containing nnrti with rt...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01) A61K 31/513 (2006.01) A61K 31/52 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2537095

The present invention concerns combinations of a pyrimidine containing NNRTI named TMC278 with nucleoside reverse transcriptase inhibitors such as emtricitabine, lamivudine or abacavir and/or nucleotide reverse transcriptase inhibitors such as tenofovir useful for the treatment of HIV infected patients or for the prevention of HIV transmission or infection.

L'invention concerne des combinaisons d'une pyrimidine renfermant NNRTI dénommée TMC278 avec des inhibiteurs nucléosidiques de la transcriptase inverse du type emtricitabine, lamivudine ou abacavir et/ou des inhibiteurs nucléotidiques de la transcriptase inverse du type tenofovir, utiles pour le traitement de patients infectés par le VIH ou pour la prévention de la transmission du VIH ou de l'infection par le VIH.

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