A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/42 (2006.01) A61K 31/195 (2006.01) A61K 31/4245 (2006.01) A61P 19/02 (2006.01)
Patent
CA 2476438
The invention relates to a combination, comprising a selective inhibitor of COX-2, or a phamaceutically acceptable salt thereof, and an Alpha-2-delta ligand, or a pharmaceutically acceptable salt thereof, and valdecoxib. Examples of slective inhibitors of COX-2 include valdecoxib, rofecoxib, and celecoxib. Exampoes of Alpha-2 delta ligands include gabapentin, pregabalin (3S, 4S)-(1-Aminomethyl-3,4-dimethyl-cyclopentyl)-acetic acid, and 3-(1- aminomethyl-cyclohexymethyl)-4H-[1,2,4]oxadiazol-5-one hydrochloride. The combinations are useful for treating certain diseases inclduing cartilage damage, inflammation, pain, and arthritis.
La présente invention a trait à une combinaison, comportant un inhibiteur sélectif de COX-2, ou un sel pharmaceutiquement acceptable de celui-ci, et un ligand alpha-2-delta, ou un sel pharmaceutiquement acceptable de celui-ci, et du valdécoxib. Des exemples d'inhibiteurs sélectifs de COX-2 comprennent le valdécoxib, le réfocoxib, et le célécoxib. Des exemples de ligands alpha-2-delta comprennent la gabapentine, la prégabaline, l'acide acétique de (3S, 4S)-(1-aminométhyl-3,4-diméthyle-cyclopentyle), et le chlorhydrate de 3-(1-aminométhyl-cyclohexyméthyl)-4H-[1,2,4]oxadiazol-5-one. Ces combinaisons sont utiles pour le traitement de certaines maladies comprenant la détérioration du cartilage, l'inflammation, la douleur, et l'arthrite.
Smart & Biggar
Warner-Lambert Company Llc
LandOfFree
Combinations of an alpha-2-delta ligand with a selective... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Combinations of an alpha-2-delta ligand with a selective..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Combinations of an alpha-2-delta ligand with a selective... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1488985