Combinations of bile acid sequestrant(s) and sterol...

Details Combinations of bile acid sequestrant(s) and sterol... Combinations of bile acid sequestrant(s) and sterol...

A - Human Necessities

61

K

A61K 45/06 (2006.01) A61K 31/337 (2006.01) A61K 31/395 (2006.01) A61K 31/397 (2006.01) A61K 31/455 (2006.01) A61K 31/655 (2006.01) A61K 31/7052 (2006.01) A61K 31/74 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2434033

The present invention provides compositions, therapeutic combinations and methods including: (a) at least one bile acid sequestrant; and (b) at least one substituted azetidinone or substituted .beta.-lactam sterol absorption inhibitor which can be useful for treating vascular conditions, diabetes, obesity and lowering plasma levels of sterols.

L'invention concerne des compositions, des combinaisons thérapeutiques et des procédés reposant sur l'utilisation: (a) d'au moins un chélateur des acides biliaires; et (b) d'au moins un inhibiteur d'absorption des stérols d'azétidinone ou de bêta-lactamine à substitution. Ces compositions, combinaisons thérapeutiques et procédés peuvent être utiles pour le traitement des troubles vasculaires, du diabète ou de l'obésité et pour la réduction du degré de concentration plasmique des stérols.

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