Combinations of cholesteryl ester transfer protein...

A - Human Necessities – 61 – K

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A61K 31/4965 (2006.01) A61K 31/455 (2006.01) A61K 45/06 (2006.01) A61P 3/04 (2006.01)

Patent

CA 2356158

The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia, atherosclerosis, or hyperlipidemia. Combinations disclosed include a nicotinic acid derivative combined with a cholesteryl ester transfer protein (CETP) inhibitor.

La présente invention concerne des combinaisons de composés de thérapie cardio-vasculaire utilisées pour la prévention ou le traitement de troubles cardio-vasculaires telles que l'hypercholestérolémie, l'athérosclérose ou l'hyperlipémie. Cette invention fait intervenir des combinaisons comprenant un dérivé de l'acide nicotinique combiné avec un inhibiteur de la protéine de transfert du cholestéryle-ester (cholesteryl ester transfer protein / CETP).

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