Combinations of cox-2 inhibitors and other agents for the...

A - Human Necessities – 61 – K

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A61K 31/535 (2006.01) A61K 31/18 (2006.01) A61K 31/196 (2006.01) A61K 31/34 (2006.01) A61K 31/35 (2006.01) A61K 31/352 (2006.01) A61K 31/365 (2006.01) A61K 31/381 (2006.01) A61K 31/382 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/4375 (2006.01) A61K 31/4427 (2006.01) A61K 31/444 (2006.01) A61K 31/47 (2006.01) A61K 31/50 (2006.01) A61K 31/52 (2006.01) A61K 31/5375 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2481934

A method of treating, preventing, or inhibiting PD, in a subject in need of such treatment, inhibition or prevention. The method comprises, treating the subject with one or more cyclooxygenase-2 selective inhibitor(s) or isomer(s) or pharmaceutically acceptable salt(s), ester(s), or prodrug(s) thereof, in combination with one or more second drugs, wherein the amount of the cyclooxygenase-2 selective inhibitor(s) or isomer(s) or pharmaceutically acceptable salt(s), ester(s), or prodrug(s) thereof in combination with the amount of second drug(s) constitutes a PD treatment, inhibition or prevention effective amount.

L'invention concerne une méthode de traitement, de prévention, ou d'inhibition de la maladie de Parkinson, chez un sujet nécessitant ce traitement, son inhibition ou sa prévention. Cette méthode consiste à traiter le sujet à l'aide d'un ou de plusieurs inhibiteurs sélectifs de cyclooxygénase-2, ou d'un ou de plusieurs isomères, ou d'un ou de plusieurs sels pharmaceutiquement acceptables, ou d'un ou de plusieurs esters, ou d'un ou de plusieurs promédicaments de ceux-ci, en combinaison avec un ou avec plusieurs seconds médicaments, la quantité d'inhibiteur(s) sélectif(s) de cyclooxygénase-2, ou d'isomère(s), de sel(s) pharmaceutiquement acceptable(s), d'ester(s) ou de promédicament(s) de ceux-ci, combiné à la quantité de second(s) médicament(s), constituant une dose efficace pour le traitement, l'inhibition ou la prévention de la maladie de Parkinson.

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