Combinations of growth regulating factors and hormones for...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2507470

The invention relates to the field of immunology, endocrinology and oncology and, in particular, the generation of a combined immune response to determined growth factors and hormones. A synergic effect, outlined herein, between growth regulating factors (EGF, TGF and VEGF) and hormones involved in the sexual hormones release cascade or reproduction (GnRH, LH, FSH) stimulates the anti-tumor response which is expressed as a reduction in the tumor mass and an increase in the survival time.

La présente invention concerne le domaine de l'immunologie, de l'endocrinologie et de l'oncologie, et en particulier, la génération d'une réponse immune combinée à des facteurs de croissance et à des hormones déterminés. Un effet synergique entre les facteurs régulateurs de croissance (EGF, TGF, VEGF) et les hormones impliquées dans la cascade de libération des hormones sexuelles ou reproductrices (GnRH, LH, FSH), découvert ici, favorise la réponse antitumorale, s'exprimant par une réduction de la masse tumorale et une augmentation de la durée de survie.

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