Combinations of jak inhibitors and at least one of bcr-abl,...

Details Combinations of jak inhibitors and at least one of bcr-abl,... Combinations of jak inhibitors and at least one of bcr-abl,...

A - Human Necessities

61

K

A61K 31/277 (2006.01) A61K 31/4025 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2586605

The invention provides a pharmaceutical combination comprising: a) at least one agent selected from Bcr-Abl, Flt-3, FAK and RAF kinase inhibitors; and b) at least one JAK kinase inhibitor and a method for treating or preventing a proliferative disease using such a combination.

L'invention concerne une combinaison pharmaceutique qui comprend : a) au moins un agent sélectionné dans le groupe comprenant : inhibiteurs de Bcr-Abl, inhibiteurs de Flt-3, et inhibiteurs de kinase FAK et RAF ; et b) au moins un inhibiteur de kinase JAK. L'invention concerne également un procédé permettant de traiter ou de prévenir une maladie proliférative au moyen de ladite combinaison.

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