Combinations of lipid modulating agents and substituted...

A - Human Necessities – 61 – P

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A61P 9/00 (2006.01) A61K 31/397 (2006.01) A61K 45/06 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2544309

The present invention provides compositions, therapeutic combinations and methods including: (a) at least one lipid modulating agent; and (b) at least one substituted azetidinone or substituted -lactam sterol absorption inhibitor which can be useful for treating vascular conditions, diabetes, obesity and lowering plasma levels of sterols or 5.alpha.-stanols.

La présente invention concerne des compositions, des combinaisons thérapeutiques et des méthodes comprenant: (a) au moins un modulateur lipidique; et (b) au moins une azétidinone substituée ou un inhibiteur d'absorption du stérol de .beta.-lactame substitué pouvant être utilisé pour traiter des affections vasculaires, des diabètes, l'obésité et pour abaisser les concentrations plasmiques des stérols ou des 5 .alpha.-stanols.

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