Combinations of mek inhibitors and raf kinase inhibitors and...

Details Combinations of mek inhibitors and raf kinase inhibitors and... Combinations of mek inhibitors and raf kinase inhibitors and...

A - Human Necessities

61

K

A61K 31/18 (2006.01) A61K 31/4412 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2694646

This invention concerns combinations of inhibitors of MEK, Raf protein kinases, and other kinases includin VEG-FR1 -3 and PDGFR-.beta... This invention also concerns pharmaceutical compositions comprising the compounds described herein and methods of use of the compounds and compositions described herein, including the use in the treatment and/or prevention of cancer and other hyperproliferative disorders.

L'invention concerne des combinaisons d'inhibiteurs de MEK, de protéine kinases de Raf et d'autres kinases comprenant VEGFR1-3 et PDGFR-ß. La présente invention concerne également des compositions pharmaceutiques comprenant les composés et les procédés d'utilisation des composés et des compositions décrits ici, y compris l'utilisation dans le traitement et/ou la prévention du cancer et d'autres troubles hyperprolifératifs.

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