Combinations of nicotinic acid and derivatives thereof and...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61K 31/337 (2006.01) A61K 31/395 (2006.01) A61K 31/397 (2006.01) A61K 31/455 (2006.01) A61K 31/655 (2006.01) A61K 31/7052 (2006.01) A61K 31/74 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2434488

The present invention provides compositions, therapeutic combinations and methods including: (a) at least one of nicotinic acid or derivatives thereof; and (b) at least one substituted azetidinone or substituted b-lactam sterol absorption inhibitor which can be useful for treating vascular conditions, diabetes, obesity and lowering plasma levels of sterols.

L'invention concerne des procédés, compositions et combinaisons thérapeutiques renfermant a) au moins un élément parmi l'acide nicotinique et des dérivés de ce dernier et b) au moins un inhibiteur d'absorption de stérols azétidinone substitué ou .beta.-lactame substitué pouvant être utile pour traiter des conditions vasculaires, le diabète, l'obésité et pour abaisser la concentration plasmique de stérols.

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