Combinations of polyene fungicide with cationic surfactants

A - Human Necessities – 01 – N

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A01N 43/90 (2006.01) A01N 25/30 (2006.01) A01N 47/44 (2006.01) A01P 1/00 (2006.01) A01P 3/00 (2006.01) A23C 19/11 (2006.01) A23L 3/3463 (2006.01)

Patent

CA 2695343

A solid composition comprising a cationic surfactant, such as the ethyl ester of the lauramide of the arginine monohydrochloride (LAE) and a polyene fungicide such as natamycin is provided. The solid composition is the basis for providing solutions of natamycin of increased concentration. The solid composition may be used for providing a dispersion of natamycin in a suitable liquid, such as tap water or an organic solvent. The dispersion may be further diluted with water. This leads to a solution of natamycin in water. The combination of the cationic surfactant and the polyene fungicide displays a biological effect which is stronger than the effect of each of the two components alone.

L'invention concerne une composition solide comprenant un tensioactif cationique, tel que l'ester éthylique du lauramide du monochlorhydrate d'arginine (LAE) et un fongicide de type polyène tel que la natamycine. La composition solide est la base pour produire des solutions de natamycine de concentration accrue. La composition solide peut être utilisée pour produire une dispersion de natamycine dans un liquide approprié, tel que de l'eau du robinet ou un solvant organique. La dispersion peut être encore diluée avec de l'eau. Ceci conduit à une solution de natamycine dans l'eau. L'association du tensioactif cationique et du fongicide de type polyène présente un effet biologique qui est plus fort que l'effet de chacun des deux composants seul.

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