Combinations of protein farnesyltransferase and hmg coa...

Details Combinations of protein farnesyltransferase and hmg coa... Combinations of protein farnesyltransferase and hmg coa...

A - Human Necessities

61

K

A61K 31/4164 (2006.01) A61K 45/06 (2006.01) C07D 233/54 (2006.01) C07K 5/06 (2006.01) C07K 5/08 (2006.01)

Patent

CA 2331295

Novel combinations of inhibitors of protein farnesyltransferase enzymes and HMG CoA reductases enzymes are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in preventing or treating cancer, restenosis, psoriasis, endometriosis, atherosclerosis, or viral infections.

La présente invention concerne de nouvelles combinaisons d'inhibiteurs des enzymes protéine farnésyltransférase et HMG CoA réductase, aussi bien que leurs procédés de préparation et leurs compositions pharmaceutiques, qui sont utiles en vue de prévenir ou de traiter le cancer, la resténose, le psoriasis, l'endométriose, l'athérosclérose ou des infections virales.

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