Combinations of tumor-associated antigens for the treatment...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61K 31/7088 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2529056

Disclosed herein are methods and compositions for inducing an immune response against various combinations of tumor-associated antigens, which can promote effective immunologic intervention in pathogenic processes. Embodiments of the invention disclosed herein are directed to the use of effective combinations of TuAAs for the immunotherapy of patients with various types of cancer. Both immunogenic compositions for inducing an immune response to these combinations of antigens and methods for their use are disclosed.

L'invention concerne des méthodes et des compositions permettant d'induire une réponse immune contre diverses combinaisons d'antigènes associés à des tumeurs, lesquelles permettent de favoriser une intervention immunologique efficace dans des processus pathogènes. Les modes de réalisation de l'invention ici décrite prévoient l'utilisation de combinaisons efficaces de TuAAs pour l'immunothérapie de patients atteints de divers types de cancers. Les deux compositions immunogènes destinées à induire une réponse immune à ces combinaisons d'antigènes et leurs méthodes d'utilisation sont présentées.

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