Combinatorial 1,4-benzodiazepin-2,5-dione library

Details Combinatorial 1,4-benzodiazepin-2,5-dione library Combinatorial 1,4-benzodiazepin-2,5-dione library

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) C07D 243/14 (2006.01)

Patent

CA 2226691

A method has now been found of synthesizing a combinatorial library of 1,4-benzodiazepin-2,5-diones on solid supports via an aza-Wittig ring closure, said compounds optionally encoded with tags, and to the use of this library in assays to discover biologically active compounds, and, optionally, to cleave 1,4-benzodiazepin-2,5-diones therefrom.

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