Combinatorial antisense library

Details Combinatorial antisense library Combinatorial antisense library

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C07H 21/04 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2304798

Combinatorial libraries comprise first oligonucleotide analogs and second oligonucleotide analogs which are coupled together to form antisense molecules capable of binding target polynucleotides and activating an RNase, and ribozymes capable of cleaving polynucleotides.

Bibliothèques combinatoires qui comportent des premiers analogues d'oligonucléotides et des seconds analogues d'oligonucléotides qui sont couplés ensemble pour former des molécules antisens capables de se lier à des polynucléotides cibles et d'activer une RNase, et ribozymes capables de cliver des polynucléotides.

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