A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/04 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) C07K 1/04 (2006.01)
Patent
CA 2341969
Provided herein are combinatorial libraries containing compounds of formula (1): A-(B)n-C, wherein: A is a chelator complexed to metal or radionuclide metal; B is a spacer group; n is selected from the integers 0 and 1; and C comprises a mixture of potential targeting molecules. These libraries are useful in identifying labelled compounds which exhibit a desired targeting activity.
L'invention se rapporte à des banques de composés de combinaison représentés par la formule (1): A-(B)¿n?-C, dans laquelle A est un agent chélatant formant un complexe avec un métal ou un radionucléide de métal; B est un groupe espaceur; n est choisi parmi les entiers 0 et 1 et C comporte un mélange de molécules de ciblage potentielles. Ces banques s'avèrent utiles à l'identification de composés marqués qui présentent une activité de ciblage souhaitée.
Pollak Alfred
Roe David
Thornback John
Wong Ernest
Bracco International B.v.
Pollak Alfred
Roe David
Thornback John
Torys Llp
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