Combinatorial synthesis of multibinding libraries

Details Combinatorial synthesis of multibinding libraries Combinatorial synthesis of multibinding libraries

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/00 (2006.01) A61K 47/48 (2006.01) C07B 61/00 (2006.01) C07C 215/60 (2006.01) C07C 217/08 (2006.01) C07C 233/36 (2006.01) C07C 233/78 (2006.01) C07C 237/24 (2006.01) C07C 271/20 (2006.01) C07C 323/62 (2006.01) C07C 335/08 (2006.01) C07C 335/32 (2006.01) C07D 207/09 (2006.01) C07D 207/333 (2006.01) C07D 209/48 (2006.01) C07D 211/42 (2006.01) C07D 211/56 (2006.01) C07D 211/58 (2006.01) C07D 213/74 (2006.01) C07D 213/80 (2006.01) C07D 215/56 (2006.01) C07D 233/90 (2006.01) C07D 235

Patent

CA 2318547

Disclosed are methods for synthesizing large collections of diverse multimeric compounds as well as iterative processes for evaluating key molecular constraints imparting multibinding properties to multimeric compounds. Also disclosed are libraries of multimeric compounds which can be evaluated for imparting multibinding properties.

L'invention concerne des méthodes de synthèse de grandes collections de composés multimères divers ainsi que des procédés itératifs d'évaluation de contraintes moléculaires clés conférant des propriétés de multiliaison à des composés multimères. L'invention concerne également des banques de composés multimères pouvant être évaluées afin de conférer des propriétés de multiliaison.

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