Combinatorial synthesis on support

B - Operations – Transporting – 01 – J

Patent

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Details

B01J 19/00 (2006.01)

Patent

CA 2530604

Methods are disclosed for providing a library of composite or novel composition samples on a support. The method involves depositing one or more components as concentration gradients on the surface of the support. The concentration gradients are placed on the support in the form of superimposed triangles which allow ready formation of composite or composition samples containing three or more components. The samples can be removed from the support by drilling out portions of the coated support so as to yield individual tablets containing the support with one or more component layers thereon. By using this method, a vast number of samples can be made.

La présente invention se rapporte à des procédés consistant à placer une bibliothèque d'échantillons de compositions composites ou nouvelles sur un support. Un tel procédé consiste à déposer un ou plusieurs composants utilisés en tant que gradients de concentration à la surface du support. Ces gradients de concentration sont placés sur le support sous la forme de triangles superposés qui facilitent la formation d'échantillons composites ou de compositions contenant au moins trois composants. Les échantillons peuvent être retirés du support par perçage de parties du support recouvert afin de produire des pastilles individuelles contenant le support sur lequel sont présentes une ou plusieurs couches de composants. La mise en oeuvre de ce procédé permet l'obtention d'un très grand nombre d'échantillons.

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