C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/54 (2006.01) C12M 1/40 (2006.01) C12Q 1/34 (2006.01) G01N 21/00 (2006.01) G01N 33/52 (2006.01) G01N 33/66 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2215914
The present invention is directed to a single test system and method for determining the integrated glycemic condition of a subject by measuring the concentration of glucose and the level of protein-bound glucose in a subject's body fluid, such as whole blood. The glucose concentration is indicative of the subject's immediate glycemic condition, whereas the protein-bound glucose concentration is indicative of either intermediate or long-term glycemic condition. Optionally, other analytes indicative of glycemie condition, such as ketone bodies or fatty acid derivatives, can also be measured. The present invention also provides a method of diagnosing diabetes. The invention additionally provides a method for analyzing the concentration of fructosamine in less than or equal to five minutes without the use of a reaction accelerator.
Système et méthode permettant de déterminer par un test unique la glycémie complète d'un patient en mesurant la concentration de glucose et le taux de glucose lié aux protéines dans un fluide corporel du patient, comme le sang entier. La concentration de glucose est un indicateur de l'état immédiat du patient sur le plan de la glycémie, tandis que la concentration de glucose liée aux protéines est un indicateur de la glycémie à moyen terme ou à long terme. Il est également possible de mesurer éventuellement d'autres substances indicatrices de la glycémie, comme les corps cétoniques ou les dérivés d'acides gras. L'invention porte également sur une méthode de diagnostic du diabète. Elle propose en outre une méthode d'analyse de la concentration de fructosamine en 5 minutes ou moins n'impliquant pas l'utilisation d'un accélérateur de réaction.
Burd John F.
Galen Robert S.
Hoblitzell Talei
Neyer Gebhard
Gowling Lafleur Henderson Llp
Lxn Corporation
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