A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4015 (2006.01) A61J 3/07 (2006.01) A61P 25/08 (2006.01)
Patent
CA 2603316
The invention relates to a process for the solid oral pharmaceutical formulation of a pharmaceutically active ingredient such as levetiracetam, comprising a wet granulation of the pharmaceutically active ingredient and simultaneous fluid bed drying such that, as the pharmaceutical blend granulates it is simultaneously dried thus preventing it from becoming a paste. The invention therein thus provides a novel formulation preparation process characterized by a "combined" Granulation and Fluid Bed Drying process step.
La présente invention concerne un processus pour la formulation pharmaceutique oral solide d~un ingrédient pharmaceutiquement actif tel que le lévétiracetam, comprenant une granulation par voie humide de l~ingrédient pharmaceutiquement actif et un séchage simultané à lit fluidisé, de sorte que lorsque le mélange pharmaceutique granule, il est simultanément séché, ce qui l'empêche de se transformer en pâte. Cette invention décrit donc un nouveau processus de préparation de formulation, caractérisé par une étape « combinée» comprenant un processus de granulation et un processus de séchage à lit fluidisé.
Al-Bargash Lina
Caron David A.
Genpharm Inc.
Mylan Pharmaceuticals Ulc
Osler Hoskin & Harcourt Llp
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