Combined therapies of antipsychotic drugs and tetracyclines...

A - Human Necessities – 61 – K

Patent

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A61K 45/06 (2006.01)

Patent

CA 2666796

The present invention provides combinations of an antipsychotic drug and a tetracycline, particularly minocycline, for the treatment of psychotic disorders, particularly schizophrenia. The invention also provides formulations wherein the release of one or both of the antipsychotic drug and the tetracycline is modified. The invention also provides methods using the combined therapy for treatment of psychotic disorders, particularly schizophrenia, comprising an antipsychotic drug and a tetracycline.

La présente invention concerne des combinaisons d'un médicament antipsychotique et d'une tétracycline, notamment la minocycline, utilisées pour le traitement des troubles psychiatriques, plus particulièrement la schizophrénie. Cette invention porte également sur des formulations dans lesquelles la libération d'au moins une des deux substances telles que le médicament antipsychotique et la tétracycline est modifiée; et porte sur des méthodes d'utilisation de la thérapie combinée dans le traitement des troubles psychotiques, notamment la schizophrénie, au moyen d'un médicament antipsychotique et d'une tétracycline.

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