Combined therapy against tumors comprising substituted...

Details Combined therapy against tumors comprising substituted... Combined therapy against tumors comprising substituted...

A - Human Necessities

61

K

A61K 45/06 (2006.01) A61K 31/4025 (2006.01) A61K 31/555 (2006.01) A61K 33/24 (2006.01)

Patent

CA 2410160

The present invention provides the combined use of acryloyl distamycin derivatives, in particular .alpha.-bromo- and .alpha.-chloro-acryloyl distamycin derivatives of formula (I), as set forth in the specification, and an alkylating agent, in the treatment of tumors. Also provided is the use of the said combination in the treatment or prevention of metastasis or in the treatment of tumors by inhibition of angiogenesis.

La présente invention concerne une polythérapie anticancéreuse associant des dérivés de distamycine à substitution acryloyle, en particulier des dérivés de distamycine .alpha.-bromo- et .alpha.-chloro-acryloyle représentés par la formule (I), tel que décrit dans le descriptif, et un agent alkylant. Par ailleurs, cette invention concerne l'utilisation de cette polythérapie dans le traitement ou la prévention des métastases ou dans le traitement des tumeurs par inhibition de l'angiogenèse.

Affiliated with

Also associated with

Rating

Combined therapy against tumors comprising substituted... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Combined therapy against tumors comprising substituted..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Combined therapy against tumors comprising substituted... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1462277