A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/13 (2006.01) A61K 31/198 (2006.01) A61K 31/405 (2006.01) A61K 31/436 (2006.01) A61K 45/08 (2006.01) A61P 37/06 (2006.01)
Patent
CA 2533649
The present invention provides compositions and methods for the treatment of graft rejection associated with transplantation of tissues and organs. More specifically, the compositions and methods of the present invention relate to combined treatment involving at least one agent selected from Copolymer 1, a copolymer 1-related heteropolymer or an ordered peptide in combination with at least one additional known immunosuppressive agent. The present invention also provides compositions and methods for the treatment of graft rejection using ordered peptides or ordered copolymer 1-related heteropolymers as monotherapy.
La présente invention concerne des compositions et procédés permettant de traiter le rejet d'une greffe lié à une transplantation de tissus et d'organes. Plus particulièrement, les compositions et les procédés selon la présente invention concernent un traitement combiné englobant au moins un agent sélectionné parmi le copolymère 1, un hétéropolymère lié 1 au copolymère ou un peptide ordonné en association avec au moins un agent immuno-suppresseur connu supplémentaire. La présente invention concerne des compositions et des procédés permettant le traitement du rejet de greffe à l'aide de peptides ordonnés ou d'hétéropolymères liés 1 au copolymère ordonné comme monothérapie.
Aharoni Rina
Arnon Ruth
Sela Michael
Yussim Alex
Ltd. Yeda Research And Development Co.
Mor - Research Applications Ltd.
Ridout & Maybee Llp
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