Combined use of angiogenesis inhibitor and taxane

Details Combined use of angiogenesis inhibitor and taxane Combined use of angiogenesis inhibitor and taxane

C - Chemistry, Metallurgy

07

D

C07D 215/48 (2006.01) A61K 31/337 (2006.01) A61K 31/47 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2713930

The problems of the present invention are to find a pharmaceutical composition and a method for treating cancer that exhibit excellent anti-tumor effect. Excellent anti--tumor effect is achieved when 4-(3-chloro-4--(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6- quinolinecarboxamide, an analogous compound thereof, a pharmacologically acceptable salt thereof or a solvate thereof is used in combination with taxane.

L'objet est de découvrir une composition pharmaceutique présentant un excellent effet antitumoral et un procédé thérapeutique pour le cancer. Le 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophénoxy)-7-méthoxy-6-quinoléinecarboxamide, un composé analogue ou l'un de ses sels pharmacologiquement acceptables, ou un solvate du composé ou du composé analogue ou du sel pharmacologiquement acceptable peut présenter un excellent effet antitumoral lorsqu'il est utilisé en combinaison avec un taxane.

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