Combined use of cholestanol derivative

Details Combined use of cholestanol derivative Combined use of cholestanol derivative

A - Human Necessities

61

K

A61K 31/704 (2006.01) A61K 31/282 (2006.01) A61K 31/337 (2006.01) A61K 31/7072 (2006.01) A61K 33/24 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07J 9/00 (2006.01)

Patent

CA 2717135

The invention provides a cancer chemotherapeutic agent which has fewer side effects and excellent efficacy. The cancer chemotherapeutic agent of the invention includes a cholestanol derivative represented by formula (1): Image (wherein G represents G1cNAc-Gal-, G1cNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal-, or G1cNAc-) or a cyclodextrin inclusion compound thereof, and an anti-cancer agent.

La présente invention concerne un agent chimiothérapeutique contre le cancer ayant des effets secondaires moindres et une excellente efficacité. La présente invention concerne spécifiquement un agent chimiothérapeutique contre le cancer qui est obtenu par combinaison d'un dérivé de cholestanol représenté par la formule générale (1) ou d'un clathrate de cyclodextrine de celui-ci avec un agent antitumoral. [Dans la formule, G représente GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal- ou GlcNAc-.]

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