C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2532926
The invention provides optimized methods and compositions for enhancing the immune response caused by immunostimulatory compounds used for the treatment of disease such as, but not limited to, treatment of cancer, autoimmune disorders, asthma, respiratory allergies, food allergies and infectious diseases in a patient. The optimized methods according to the invention provide synergy between the therapeutic effects of immunostimulatory oligonucleotides and immunomer compounds in accordance with the invention, and the therapeutic effect of cytokine immunotherapy and/or chemotherapeutic agents and/or radiation.
La présente invention concerne des procédés et des compositions optimisés destinés à renforcer la réponse immunitaire provoquée par des composés immunostimulatoires utilisés dans le traitement de maladies telles que, de manière non limitative, le cancer, les affections autoimmunes, l'asthme, les allergies respiratoires, les allergies alimentaires et les maladies infectieuses chez un patient. Les procédés optimisés de l'invention entraînent une synergie entre les effets thérapeutiques des oligonucléotides immunostimulatoires et les composés immunomères de l'invention, et l'effet thérapeutique de l'immunothérapie aux cytokines et/ou des agents chimiothérapeutiques et/ou des rayonnements.
Agrawal Sudhir
Kandimalla Ekambar R.
Benoit & Cote Associes Inc.
Hybridon Inc.
Idera Pharmaceuticals Inc.
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