C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/63 (2006.01) A01K 67/027 (2006.01) A61K 38/18 (2006.01) A61K 38/22 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01) C07K 14/50 (2006.01) C07K 14/595 (2006.01) C12N 15/09 (2006.01) C12N 15/16 (2006.01) C12N 15/18 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2522895
The invention relates generally to compositions, conjugates, and methods comprising a KGF agonist and a gastrin compound. The compositions can be used in the treatment and/or prevention of conditions for which either a KGF agonist or a gastrin compound have been demonstrated to have a therapeutic effect, including but not limited to diabetes, hypertension, chronic heart failure, fluid retentive states, metabolic syndrome and related diseases and disorders, and obesity.
De manière générale, la présente invention a trait à des compositions, des conjugués, et des procédés comportant un agoniste de facteur de croissance de kératinocytes et un composé de gastrine. Les compositions peuvent être utilisées dans le traitement et/ou la prévention de conditions pour lesquelles soit un agoniste de facteur de croissance de kératinocytes ou un composé de gastrine ont révélé un effet thérapeutique, comprenant, mais de manière non exclusive, le diabète, l'hypertension, l'insuffisance cardiaque chronique, des états de rétention de fluides, le syndrome métabolique et des maladies et troubles associés, et l'obésité.
Brand Stephen J.
Cruz Antonio
Mccarthy Tetrault Llp
Waratah Pharmaceuticals Inc.
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