A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4422 (2006.01) A61K 31/4178 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 13/12 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2514921
A medicine for the prevention of and/or treatments for arteriosclerosis, hypertension, cardiac diseases, kidney diseases, or cerebrovascular diseases. It comprises the following ingredients as active ingredients: (A) an angiotensin II receptor antagonist selected from the group consisting of the compound represented by the following formula (I), (I) pharmacologically acceptable esters thereof, and pharmacologically acceptable salts of these (e.g., olmesartan medoxomil); and (B) a calcium antagonist selected from the group consisting of 1,4-dihydropyridine compounds and pharmacologically acceptable salts of these (e.g., azelnidipine).
L'invention concerne un médicament pour la prévention et/ou le traitement de l'artériosclérose, de l'hypertension, de maladies cardiaques, de maladies des reins ou de maladies vasculaires cérébrales. Le médicament selon l'invention comprend les constituants suivants comme constituants actifs : (A) un antagoniste du récepteur de l'angiotensine II, sélectionné dans le groupe comprenant le composé de formule (I), des esters pharmacologiquement acceptables de ce composé et des sels pharmacologiquement acceptables de ceux-ci (par exemple, olmésartan, médoxomil), ainsi que (B) un antagoniste du calcium sélectionné dans le groupe comprenant des composés 1,4-dihydropyridine et des sels pharmacologiquement acceptables de ces composés (par exemple, azelnidipine).
Horiuchi Masatsugu
Iwai Masaru
Mizuno Makoto
Sada Toshio
Daiichi Sankyo Company Limited
Marks & Clerk
Sankyo Company Limited
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