Compartment segregation by pixel characterization using...

G - Physics – 06 – K

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G06K 9/00 (2006.01) G01N 21/00 (2006.01) G06T 7/00 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2690612

The present invention relates generally to improved methods of defining areas or compartments within which biomarker expression is detected and quantified. In particular, the present invention relates to automated methods for delineating marker- defined compartments objectively with minimal operator intervention or decision making. The method provides for precise definition of tissue, cellular or subcellular compartments particularly in histological tissue sections in which to quantitatively analyzing protein expression.

La présente invention concerne en général des procédés améliorés pour définir des zones ou compartiments à l'intérieur desquels une expression d'un biomarqueur est détectée et quantifiée. La présente invention concerne en particulier des procédés automatisés pour définir des compartiments définis par des marqueurs de manière objective avec une intervention ou prise de décision minimale de l'opérateur. Le procédé prévoit une définition précise de compartiments cellulaires ou sous-cellulaires de tissu, en particulier dans des sections de tissu histologique dans lesquelles analyser quantitativement une expression protéique.

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