Compatible display vector systems

Details Compatible display vector systems Compatible display vector systems

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01)

Patent

CA 2736904

The present invention provides a polynucleotide vector system used during polypeptide display that can be used to facilitate transfer of pools of polynucleotides encoding antigen binding proteins of interest. The present invention also provides methods that allow seamless conversion of pools of polynucleotides encoding antigen binding proteins using a restriction enzyme digestion and ligation strategy.

Cette invention concerne un système de vecteur polynucléotidique utilisé lors de la présentation de polypeptides qui peut être utilisé pour faciliter le transfert de groupes de polynucléotides codant pour des protéines se liant à l'antigène d'intérêt. La présente invention concerne également des procédés qui permettent la conversion homogène de groupes de polynucléotides codant pour des protéines se liant à l'antigène au moyen d'une stratégie de digestion par enzymes de restriction et ligature.

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