Compatible display vector systems

Details Compatible display vector systems Compatible display vector systems

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C12N 15/72 (2006.01)

Patent

CA 2737752

The present invention provides a polynucleotide vector system used during polypeptide display that can be used to facilitate transfer of pools of polynucleotides encoding antigen binding proteins of interest. The present invention also provides methods that allow seamless conversion of pools of polynucleotides encoding antigen binding proteins using a restriction enzyme digestion and ligation strategy.

La présente invention concerne un système de vecteurs de polynucléotides utilisé pendant la présentation de polypeptides, qui peut être utilisé pour faciliter le transfert de banques de polynucléotides codant pour des protéines de liaison à lantigène dintérêt. La présente invention concerne également des procédés qui permettent une conversion continue de banques de polynucléotides codant pour des protéines de liaison à lantigène, qui utilisent une stratégie de ligature et de digestion dune enzyme de restriction.

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