Competitive fluorimetric immunoassay for a hydantoin

G - Physics – 01 – N

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167/43

G01N 33/53 (2006.01) G01N 33/94 (2006.01)

Patent

CA 1087980

ABSTRACT OF THE DISCLOSURE Substituted hydantoin drugs (for example phenytoin) and tricyclic antidepressant drugs (for example nortriptyline) are assayed by mixing them with a fluorescent labelled compound and antibodies, and measuring the fluorescence of the mixture. The assay does not necessitate any separation step and may be effected by continuous-flow techniques.

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