Competitive immunoassay device

G - Physics – 01 – N

Patent

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Details

G01N 33/558 (2006.01) B01L 3/00 (2006.01) G01N 30/90 (2006.01) G01N 33/543 (2006.01) G01N 30/02 (2006.01)

Patent

CA 2221120

A chromatographic assay device for detection and/or determination of an analyte in a competitive immunoassay gives a semiquantitative or quantitative indication of analyte concentration in a single assay device while also giving a positive indication that flow has occurred properly through the device. In one form, the device comprises a first opposable component (12) including a sample preparation zone (18) and an absorber (20); and a second opposable component (14) including a first chromatographic medium (22) with capture and detection zones, a second chromatographic medium (32) with a comparison zone (38), and a comparison label zone (40).

L'invention concerne un dispositif d'essai chromatographique pour la détection et/ou la determination d'un analyte dans un dosage immunologique par compétition, qui fournit une indication semi quantitative ou quantitative de la concentration d'analyte dans un dispositif de dosage unique, qui donne également une indication positive sur le passage correct du flux dans le dispositif. Selon une variante, le dispositif comprend un premier élément opposable (12) présentant une zone de préparation des échantillons (18) et un absorbeur (20); et un second élément opposable (14) présentant un premier support chromatographique (22) doté de zones de collecte et de détection, un second support chromatographique (32) doté d'une zone de comparaison (38), et une zone de marquage de comparaison (40).

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