Complement binding aptamers and anti-c5 agents useful in the...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01)

Patent

CA 2643951

Methods of treating complement-mediated ocular disorders by administering agents that inhibit a subject's complement component in an amount sufficient to treat the ocular disorder wherein, in a selected embodiment, said agent is an anti-complement aptamer that, in a preferred embodiment, is an anti-C5 aptamer.

La présente invention concerne des procédés de traitement de troubles oculaires induits par un complément par l'administration d'agents qui inhibent le composant complément d'un sujet en une quantité suffisante pour traiter le trouble oculaire de celui-ci. Dans un mode de réalisation choisi, ledit agent est un aptamère anticomplément qui, dans un mode de réalisation préféré, est l'aptamère anti-C5.

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