Complement components and binding ligands in fertility

Details Complement components and binding ligands in fertility Complement components and binding ligands in fertility

G - Physics

01

N

G01N 33/566 (2006.01) A61D 19/02 (2006.01) A61K 38/17 (2006.01) C12N 5/08 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2077438

2077438 9113352 PCTABS00007 Methods for detecting and isolating acrosome-reacted sperm and complement receptor-bearing oocytes using the complement component C3, fragments, or variants thereof, antibodies to a complement receptor, or antibodies to C3, are disclosed. These methods have application in the assessment of fertility, in the preparation of sperm or oocytes for in vitro fertilization or for gamete intrafallopian tube transfer, in promoting or inhibiting fertilization in vitro and in vivo, and in diagnosing and treating infertility.

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