Complement inhibitors as therapeutic agents for treatment of...

A - Human Necessities – 61 – K

Patent

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A61K 39/395 (2006.01) A61K 38/08 (2006.01) A61K 38/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2718588

Methods for treating, preventing or delaying onset of tumor formation and other forms of cancer are disclosed. The methods involve administration of a complement inhibitor to inhibit C5a receptor signaling in the tumor microenvironment.

L'invention porte sur des procédés pour traiter, prévenir ou retarder le début de la formation d'une tumeur et d'autres formes de cancer. Les procédés mettent en jeu l'administration d'un inhibiteur du complément pour inhiber la signalisation du récepteur C5a dans le microenvironnement de la tumeur.

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