A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 14/00 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2505601
Modulation of the complement system represents a therapeutic modality for numerous pathologic conditions associated with complement activation. In a strategy to prepare complement inhibitors that are targeted to sites of complement activation and disease, compositions comprising a complement inhibitor linked to complement receptor (CR) 2 are disclosed. The disclosed are compositions can be used in methods of treating pathogenic diseases and inflammatory conditions by modulating the complement system.
La modulation du système complémentaire constitue une modalité thérapeutique pour de nombreux états pathologiques associés à une activation de complément. Dans une stratégie permettant de préparer des inhibiteurs de complément ciblés sur des sites d'activation de complément et de maladie, l'invention concerne des compositions comprenant un inhibiteur de complément lié au récepteur 2 de complément (CR). Lesdites compositions peuvent s'utiliser dans des méthodes de traitement de maladies pathogènes et d'états inflammatoires par modulation du système complémentaire.
Holers Michael V.
Tomlinson Stephen
Borden Ladner Gervais Llp
Musc Foundation For Research Development
Regents Of University Of Colorado
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