Complementary adenoviral vector systems and cell lines

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/861 (2006.01) C12N 5/10 (2006.01) C12N 15/64 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2192442

The present invention provides multiply deficient adenoviral vectors and complementing cell lines. Also provided are recombinants of the multiply deficient adenoviral vectors and a therapeutic method, particularly relating to gene therapy, vaccination, and the like, involving the use of such recombinants.

La présente invention concerne des vecteurs adénoviraux à déficiences multiples et des lignées cellulaires complémentaires. L'invention concerne également de tels vecteurs adénoviraux, à déficiences multiples, obtenus par recombinaison, et un procédé de traitement notamment de thérapie génique, de vaccination, ou similaire, impliquant l'utilisation de tels produits de recombinaison.

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