Complementary dna's encoding proteins with signal peptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/10 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 9/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2368098

The sequences of cDNAs encoding secreted proteins are disclosed. The cDNAs can be used to express secreted proteins or fragments thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The cDNAs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The cDNAs may also be used to design expression vectors and secretion vectors.

L'invention porte sur des séquences de protéines sécrétées codant des ADNc. Ces ADNc peuvent être utilisés pour exprimer des protéines sécrétées ou des fragments de celles-ci ou pour obtenir des anticorps capables de se lier de manière spécifique aux protéines sécrétées. Les ADNc peuvent également être utilisés dans des démarches diagnostiques, dans l'analyse génétique à des fins médico-légales, en thérapie génique et dans des méthodes de cartographie de gènes, ainsi que pour étudier les vecteurs d'expression et de sécrétion.

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