Complementary dna's encoding proteins with signal peptides

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/11 (2006.01) A61K 48/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/62 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G06F 17/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2354369

The sequences of cDNAs encoding secreted proteins are disclosed. The cDNAs can be used to express secreted proteins or fragments thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The cDNAs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. The cDNAs may also be used to design expression vectors and secretion vectors.

L'invention concerne des séquences d'ADNc codant pour des protéines sécrétées. Les cADN peuvent servir pour exprimer des protéines sécrétées ou des fragments de celles-ci ou à obtenir des anticorps capables précisément de se lier auxdites protéines. Les cADN peuvent également servir dans des opérations de diagnostic, de médecine légale, de thérapie génique et de mappage des chromosomes. On peut également les utiliser pour concevoir des vecteurs d'expression et des vecteurs de sécrétion.

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