Complex between carrageenan and a water soluble drug having...

A - Human Necessities – 61 – K

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A61K 47/36 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2307863

A complex between carrageenan and a water soluble drug characterised in powder form having an average particle size comprised between 10 and 100 µm, and the basic water drug is contained in the complex in amounts ranging from 1.5 and 5 mmol/g carrageenan, a process for preparing this complex and relative controlled release pharmaceutical compositions containing it.

L'invention concerne un complexe à base de caraghénane et d'un médicament soluble dans l'eau se présentant sous forme d'une poudre caractérisée par des particules de taille moyenne comprise entre 10 et 100 µm; ledit médicament de base soluble dans l'eau est présent dans le complexe à raison de 1,5 à 5 mmol/g par gramme de caraghénane. L'invention concerne également un procédé de préparation de ce complexe et de compositions pharmaceutiques à libération relativement contrôlée renfermant ledit complexe.

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