C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/56 (2006.01) A61K 49/00 (2006.01) G01N 33/86 (2006.01)
Patent
CA 2231354
An inhibitor bound to a substrate of high molecular weight inhibits a metabolic enzyme capable of being activated and is useful as molecular marker to determine the activation of said enzyme and diagnose the presence of said enzyme. Also disclosed is the use of a thrombin inhibitor bound to a substrate of high molecular weight as molecular marker to detect coagulation activation for the purpose of diagnosing coagulation and monitoring a therapeutic treatment. Preferably, the use of dextran-hirudine or PEG-coupled hirudine as molecular marker is disclosed for diagnosing coagulation and monitoring a therapeutic treatment.
L'invention concerne l'utilisation d'un inhibiteur d'une enzyme métabolique activable, lié à un support de poids moléculaire élevé, comme marqueur moléculaire pour déterminer l'activation de l'enzyme en vue de diagnostiquer la présence de ladite enzyme. L'invention concerne en particulier l'utilisation d'un inhibiteur de thrombine lié à un support de poids moléculaire élevé, comme marqueur moléculaire pour la détermination d'une activation de coagulation, lors du diagnostic de la coagulation et du contrôle thérapeutique. L'invention concerne de préférence l'utilisation de dextrane-hirudine ou d'hirudine accouplée au PEG, comme marqueur moléculaire pour le diagnostic de coagulation et le contrôle thérapeutique.
Baldinger Verena
Bucha Elke
Nowak Gotz
Deeth Williams Wall Llp
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
LandOfFree
Complex-bound inhibitors of metabolic enzymes capable of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Complex-bound inhibitors of metabolic enzymes capable of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Complex-bound inhibitors of metabolic enzymes capable of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2040017